Annotated protein:Gamma-aminobutyric acid receptor subunit alpha-3 (GABA(A) receptor subunit alpha-3). Gene symbol: GABRA3. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P20236
antibody wiki:
SynGO gene info:SynGO data @ GABRA3
Ontology domain:Cellular Component
SynGO term:integral component of presynaptic active zone membrane (GO:0099059)
Synapse type(s):hypothalamus, GABAergic
Annotated paper:Belenky MA, et al. "Presynaptic and postsynaptic GABAA receptors in rat suprachiasmatic nucleus" Neuroscience. 2003;118(4):909-23 PMID:12732237
Figure(s):Fig.5-7, 8e
Annotation description:Here we report on the subcellular localization of these receptors in the SCN, as revealed by an exten- sively characterized antibody to the

12/9/2017 Pim
- Literal: "GABAA-receptor immunoreactivity is associated with the terminal plasma membrane and also occupies the intercellular cleft adjacent to a GABA-negative terminal (T2) D, dendrite. (b) Three GABAergic terminals (T1, T2, T3), two of which (T1, T3) express GABAA-receptor immunoreactivity associated with the terminal plasma membrane."
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Niels Cornelisse (ORCID:0000-0001-9425-2935)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:1252
Dataset release (version):20210225
View annotation as GO-CAM model:Gene Ontology