Annotated protein:Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A). Gene symbol: GRIN2A. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q00959
antibody wiki:
SynGO gene info:SynGO data @ GRIN2A
Ontology domain:Biological Process
SynGO term:transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential (GO:1904315)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Barria A, et al. "Subunit-specific NMDA receptor trafficking to synapses" Neuron. 2002 Jul 18;35(2):345-53 PMID:12160751
Annotation description:Fig.2: Electrophysiological Tag of NMDA-R Allows Monitoring of Functional Insertion of Recombinant Receptor into Synapses.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Over-expression
Evidence tracking, Experiment Assay:Whole-cell patch clamp
Annotator(s):Pim van Nierop (ORCID:0000-0003-0593-3443)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:1970
Dataset release (version):20210225
View annotation as GO-CAM model:Gene Ontology