Annotated protein:Glutamate receptor ionotropic, kainate 4 (GluK4) (Glutamate receptor KA-1) (KA1). Gene symbol: GRIK4. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q01812
antibody wiki:
SynGO gene info:SynGO data @ GRIK4
Ontology domain:Cellular Component
SynGO term:integral component of presynaptic membrane (GO:0099056)
Synapse type(s):dorsal root ganglion (DRG), glutamatergic
Annotated paper:Lucifora S, et al. "Presynaptic low- and high-affinity kainate receptors in nociceptive spinal afferents" Pain. 2006 Jan;120(1-2):97-105 PMID:16360275
Figure(s):figure 2C
Annotation description:Immuno EM in afferent terminals of rat DRG.

8/9/2017 Pim
- Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen.
- Afferent input into DRG is known to be glutamatergic
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Niels Cornelisse (ORCID:0000-0001-9425-2935)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:1115
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology