| Annotated protein: | Syntaxin-1A (Neuron-specific antigen HPC-1) (Synaptotagmin-associated 35 kDa protein) (P35A). Gene symbol: STX1A. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P32851 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ STX1A |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of synaptic vesicle membrane (GO:0030285) |
| Annotated paper: | Boyken J, et al. "Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses" Neuron. 2013 Apr 24;78(2):285-97 PMID:23622064 |
| Figure(s): | Figure 5 |
| Annotation description: | Figure 5: The transmembrane Syntaxin 1A is enriched in the synaptic vesicle fraction |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | none of the above |
| Evidence tracking, Experiment Assay: | Biochemical fractionation (generic) |
| Annotator(s): | Ruud Toonen (ORCID:0000-0002-9900-4233) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| Additional literature: | Syntaxin1A identified in purified SV fraction (Table I) @ PMID:17110340 This paper uses immuno-EM to show syntaxin-1a expression in pre- and postsynaptic terminals of glutamatergic hippoampal neurons @ PMID:26903802 |
| SynGO annotation ID: | 1246 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |