| Annotated protein: | Sodium channel protein type 1 subunit alpha (Sodium channel protein brain I subunit alpha) (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1). Gene symbol: SCN1A. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P04774 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SCN1A |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of presynaptic membrane (GO:0099056) |
| Synapse type(s): | retina |
| Annotated paper: | Mojumder DK, et al. "Voltage-gated sodium channel alpha-subunits Na(v)1.1, Na(v)1.2, and Na(v)1.6 in the distal mammalian retina" Mol Vis. 2007 Nov 27;13:2163-82 PMID:18079688 |
| Figure(s): | Fig. 8D-F |
| Annotation description: | Localisation of Na(v)1.1 in synaptic terminals in the retina using immunohistochemistry. 6/2/2018 Pim - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Niels Cornelisse (ORCID:0000-0001-9425-2935) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 1341 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |