Annotated protein:Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A). Gene symbol: GRIN2A. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q00959
antibody wiki:
SynGO gene info:SynGO data @ GRIN2A
Ontology domain:Cellular Component
SynGO term:integral component of presynaptic membrane (GO:0099056)
Synapse type(s):Parallel fibre (cerebellum -> Purkinje-cell)
Annotated paper:Bidoret C, et al. "Presynaptic NR2A-containing NMDA receptors implement a high-pass filter synaptic plasticity rule" Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):14126-31 PMID:19666514
Figure(s):Fig. 3D-E
Annotation description:localisation of NR2A in presynapse using immuno EM.

22/11/2017 Pim
- Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Niels Cornelisse (ORCID:0000-0001-9425-2935)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:1349
Dataset release (version):20210225
View annotation as GO-CAM model:Gene Ontology