| Annotated protein: | Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2). Gene symbol: DYNLL2. Taxonomy: Homo sapiens (Human). Uniprot ID: Q96FJ2 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ DYNLL2 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Moutin E, et al. "GKAP-DLC2 interaction organizes the postsynaptic scaffold complex to enhance synaptic NMDA receptor activity" J Cell Sci. 2012 Apr 15;125(Pt 8):2030-40 PMID:22328512 |
| Figure(s): | Fig.3 |
| Annotation description: | Fig.3: "These experiments highlighted a neuronal activity-induced potentiation of GKAP-DLC2 interaction in postsynaptic elements." shown with BRET microscopy. |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Over-expression |
| Evidence tracking, Experiment Assay: | Wide-field fluorescence FRET |
| Annotator(s): | Harold MacGillavry (ORCID:0000-0002-6153-3586) Casper Hoogenraad (ORCID:0000-0002-2666-0758) |
| Lab: | Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands |
| SynGO annotation ID: | 1810 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |