Annotated protein:Gamma-aminobutyric acid receptor subunit alpha-3 (GABA(A) receptor subunit alpha-3). Gene symbol: GABRA3. Taxonomy: Mus musculus (Mouse). Uniprot ID: P26049
antibody wiki:
SynGO gene info:SynGO data @ GABRA3
Ontology domain:Biological Process
SynGO term:transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential (GO:1904315)
Synapse type(s):amygdala, GABAergic
Annotated paper:Geracitano R, et al. "Functional expression of the GABA(A) receptor alpha2 and alpha3 subunits at synapses between intercalated medial paracapsular neurons of mouse amygdala" Front Neural Circuits. 2012 May 31;6:32 PMID:22666188
Annotation description:Fig.2: "The α3 subunit selective agonist TP003 increases the decay time constant of Imp-mediated uIPSCs"
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antagonist / agonist
Evidence tracking, Experiment Assay:Whole-cell patch clamp
Annotator(s):Pim van Nierop (ORCID:0000-0003-0593-3443)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:2082
Dataset release (version):20210225
View annotation as GO-CAM model:Gene Ontology