| Annotated protein: | Gamma-aminobutyric acid receptor subunit alpha-3 (GABA(A) receptor subunit alpha-3). Gene symbol: GABRA3. Taxonomy: Mus musculus (Mouse). Uniprot ID: P26049 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ GABRA3 |
| Ontology domain: | Biological Process |
| SynGO term: | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential (GO:1904315) |
| Synapse type(s): | amygdala, GABAergic |
| Annotated paper: | Geracitano R, et al. "Functional expression of the GABA(A) receptor alpha2 and alpha3 subunits at synapses between intercalated medial paracapsular neurons of mouse amygdala" Front Neural Circuits. 2012 May 31;6:32 PMID:22666188 |
| Figure(s): | Fig.2 |
| Annotation description: | Fig.2: "The α3 subunit selective agonist TP003 increases the decay time constant of Imp-mediated uIPSCs" |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antagonist / agonist |
| Evidence tracking, Experiment Assay: | Whole-cell patch clamp |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 2082 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |