| Annotated protein: | Glutamate receptor-interacting protein 2 (GRIP-2) (AMPA receptor-interacting protein GRIP2). Gene symbol: GRIP2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q9WTW1 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ GRIP2 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic density (GO:0014069) |
| Synapse type(s): | brain |
| Annotated paper: | Dong H, et al. "Characterization of the glutamate receptor-interacting proteins GRIP1 and GRIP2" J Neurosci. 1999 Aug 15;19(16):6930-41 PMID:10436050 |
| Figure(s): | Figure 2 |
| Annotation description: | Fig.2: "Distribution and subcellular fractionation of GRIP1 and GRIP2 protein in brain" - Literal: "Treatment of synaptic plasma membrane fractions with various detergents to generate PSD fractions demonstrated that GRIP1 and GRIP2 were enriched in the PSD (Fig.2 e)" Note: the localization of GRIP2 is not as well described as of GRIP1 in this paper. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) |
| Annotator(s): | Harold MacGillavry (ORCID:0000-0002-6153-3586) Casper Hoogenraad (ORCID:0000-0002-2666-0758) |
| Lab: | Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands |
| SynGO annotation ID: | 2145 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |