Annotated protein:Glutamate receptor-interacting protein 1 (GRIP-1) (AMPA receptor-interacting protein GRIP1). Gene symbol: GRIP1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P97879
antibody wiki:
SynGO gene info:SynGO data @ GRIP1
Ontology domain:Cellular Component
SynGO term:postsynapse (GO:0098794)
Annotated paper:Dong H, et al. "GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors" Nature. 1997 Mar 20;386(6622):279-84 PMID:9069286
Figure(s):Figure 4
Annotation description:Immunostaining with an antibody specific for GRIP1 demonstrates a punctate pattern co-localizing with AMPARs at postsynaptic sites indicating that GRIP1 is enriched at postsynaptic specializations.
Evidence tracking, Biological System:Cultured neurons
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Wide-field fluorescence
Annotator(s):Harold MacGillavry (ORCID:0000-0002-6153-3586)
Casper Hoogenraad (ORCID:0000-0002-2666-0758)
Lab:Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands
SynGO annotation ID:216
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology