| Annotated protein: | Gamma-aminobutyric acid receptor subunit gamma-2 (GABA(A) receptor subunit gamma-2). Gene symbol: GABRG2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P18508 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ GABRG2 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic specialization membrane (GO:0099060) |
| Synapse type(s): | cerebellum, glutamatergic cerebellum, GABAergic |
| Annotated paper: | Nusser Z, et al. "Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells" J Neurosci. 1998 Mar 1;18(5):1693-703 PMID:9464994 |
| Figure(s): | Fig.5, 7 |
| Annotation description: | Fig.5: "An asymmetrical synapse (double arrows) made by a mossy fiber terminal (mt) with a granule cell dendrite (d) is immunopositive for the γ2 subunit. Particles also are present on the extrasynaptic dendritic membranes (arrowheads). B," Fig.7: "Colocalization of the α1 (20-nm gold), β2/3 (5-nm gold), and γ2 (10-nm gold) subunits of the GABAA receptor in Golgi synapses of the mouse cerebellum." |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 2180 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |