| Annotated protein: | Netrin-G2 (Laminet-2). Gene symbol: NTNG2. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8R4F1 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ NTNG2 |
| Ontology domain: | Biological Process |
| SynGO term: | postsynaptic specialization assembly (GO:0098698) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Kim S, et al. "NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation" Nat Neurosci. 2006 Oct;9(10):1294-301 PMID:16980967 |
| Figure(s): | fig 3, 6 |
| Annotation description: | Note: Netrin-G2; NTNG2 is a postsynaptic protein. Fig.3: "Overexpression of NGL-2 increases the number of PSD-95-positive dendritic protrusions through both PSD-95-dependent and PSD-95-independent mechanisms" Figure 6: "Direct aggregation of NGL-2 on the dendritic surface induces clustering of excitatory postsynaptic proteins" |
| Evidence tracking, Biological System: | Cultured neurons Non-neuronal tissue |
| Evidence tracking, Protein Targeting: | Over-expression |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| SynGO annotation ID: | 2765 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |