Annotated protein:Breast carcinoma-amplified sequence 1 homolog (Protein whose mRNA is enriched in synaptosomes 2) (Pmes-2). Gene symbol: BCAS1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q3ZB98
antibody wiki:
SynGO gene info:SynGO data @ BCAS1
Ontology domain:Cellular Component
SynGO term:synapse (GO:0045202)
Synapse type(s):forebrain
Annotated paper:Ishimoto T, et al. "Cloning and characterization of a novel synaptosome-enriched mRNA that encodes 31 kDa protein" Biochim Biophys Acta. 2002 Dec 12;1579(2-3):189-95 PMID:12427555
Figure(s):Fig.5
Annotation description:Fig.5: " Localization of the PMES-2 protein in a subcellular fraction"
- "The immunoreactivity for the PMES-2 was detected in forebrain homogenate, synaptosome fraction, Triton-solubilized fraction (the supernatant of the fourth centrifuge) and PSD fraction at 42 kDa (Fig. 5B). "

23/3/2018 Pim
- The WB looks so shady (could not reliably identify the PSD lane) that I did not annotate to PSD.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Western blot
Biochemical fractionation (generic)
Annotator(s):Pim van Nierop (ORCID:0000-0003-0593-3443)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:2952
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology