Annotated protein:Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2). Gene symbol: GABRB2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P63138
antibody wiki:
SynGO gene info:SynGO data @ GABRB2
Ontology domain:Cellular Component
SynGO term:integral component of presynaptic active zone membrane (GO:0099059)
Synapse type(s):globus pallidus
Annotated paper:Chen L, et al. "Subcellular localization of GABAB receptor subunits in rat globus pallidus" J Comp Neurol. 2004 Jun 28;474(3):340-52 PMID:15174078
Figure(s):Fig.5A,B,E; Fig.4, Fig. 6C,D, Fig. 8C,D
Annotation description:GABA B2 subunit detection in Globus pallidus synapses.

11/9/2017 Pim
- Literal: " At asymmetric synapses, the majority (85%) of the synapse-associated immunogold particles were located at the edges of the synapse (Fig. 5B), accounting for 34% and 51% for pre- and postsynaptic sites, respectively (Fig. 4B), with only 15% located in the main body (Fig. 5A). However, at symmetric synapses, most (89%) GABAB2 immunogold particles were localized in the main body of the synapses (Fig. 5C-E); 41% associated with the presynaptic membrane and 48% with the postsynaptic membrane (Fig. 4B)"
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Niels Cornelisse (ORCID:0000-0001-9425-2935)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:3041
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology