Annotated protein:Syntaxin-1A (Neuron-specific antigen HPC-1) (Synaptotagmin-associated 35 kDa protein) (P35A). Gene symbol: STX1A. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P32851
antibody wiki:
SynGO gene info:SynGO data @ STX1A
Ontology domain:Cellular Component
SynGO term:integral component of synaptic vesicle membrane (GO:0030285)
Synapse type(s):Schaffer collateral synapse (CA3->CA1)
Annotated paper:Hussain S, et al. "SNARE Protein Syntaxin-1 Colocalizes Closely with NMDA Receptor Subunit NR2B in Postsynaptic Spines in the Hippocampus" Front Mol Neurosci. 2016 Feb 5;9:10 PMID:26903802
Figure(s):Figures 3 5 &6
Annotation description:Figures 3A,B,D,E: Presynaptically, the highest density of syntaxin-1 immunoreactivity in the presynaptic compartment was located at the plasma membrane of the AZ. Many gold particles were also observed attached to presynaptic vesicles.
Figure 5 shows quantification of immune-gold particles at presynapse.

19/6/2018 Pim
- Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Ruud Toonen (ORCID:0000-0002-9900-4233)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:3789
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology