| Annotated protein: | ELAV-like protein 2 (Hu-antigen B) (HuB). Gene symbol: ELAVL2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q8CH84 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ ELAVL2 |
| Ontology domain: | Biological Process |
| SynGO term: | regulation of synapse assembly (GO:0051963) |
| Synapse type(s): | Cerebellar granule cell to Purkinje cell synapse |
| Annotated paper: | Yamada T, et al. "Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain" Neuron. 2014 Jul 2;83(1):122-34 PMID:24991957 |
| Figure(s): | fig 5C and 5D |
| Annotation description: | Knockdown of Elavl2 increased the density of presynaptic boutons along granule neuron parallel fibers in the cerebellum in vivo |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | RNAi / shRNA |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Alexandros Kanellopoulos (ORCID:0000-0002-2094-7491) Vittoria Mariano (ORCID:0000-0002-9848-0262) Achsel Tilmann (ORCID:0000-0002-1190-4481) Claudia Bagni (ORCID:0000-0002-4419-210X) |
| Lab: | Department of Fundamental Neurosciences, University of Lausanne, CH-1006 Lausanne, Switzerland; Dept Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy |
| SynGO annotation ID: | 3848 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |