| Annotated protein: | Neuronal membrane glycoprotein M6-a (M6a). Gene symbol: GPM6A. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q812E9 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ GPM6A |
| Ontology domain: | Cellular Component |
| SynGO term: | presynapse (GO:0098793) |
| Synapse type(s): | cerebellum, glutamatergic cerebral cortex, glutamatergic Parallel fibre (cerebellum -> Purkinje-cell) |
| Annotated paper: | Roussel G, et al. "Immunoelectron microscopic localization of the M6a antigen in rat brain" J Neurocytol. 1998 Sep;27(9):695-703 PMID:10447243 |
| Figure(s): | Fig. 5 |
| Annotation description: | Immunoelectron microscopic localization of the M6a antigen in rat brain (Fig. 5). Localization of immunoreactivity in presynaptic boutons of cerebellar parallel fibres and cerebral cortex. No immunoreactivity is observed on the postsynaptic side. Immunoactivity was detected via peroxidase activity. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
| Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
| Additional literature: | This study colocalizes endogenous M6A with pre- and postsynaptic markers in cultured hippocampal neurons. Fig. 2 @ PMID:27793698 |
| SynGO annotation ID: | 3983 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |