Annotated protein:Casein kinase II subunit beta (CK II beta). Gene symbol: CKIIBETA. Taxonomy: Drosophila melanogaster (Fruit fly). Uniprot ID: P08182
antibody wiki:
SynGO gene info:SynGO data @ CSNK2B
Ontology domain:Cellular Component
SynGO term:presynaptic cytosol (GO:0099523)
Synapse type(s):Neuro-muscular junction
Annotated paper:Bulat V, et al. "Presynaptic CK2 promotes synapse organization and stability by targeting Ankyrin2" J Cell Biol. 2014 Jan 6;204(1):77-94 PMID:24395637
Figure(s):Figure 5
Annotation description:The authors overexpressed GFP-tagged CK2b in the presynaptic neuron of the fly NMJ. GFP signal was observed in presynaptic terminals, overlapping with vGlut signals. This suggests that CK2b is localized to the presynapse.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Over-expression
Evidence tracking, Experiment Assay:Confocal
Annotator(s):Arthur de Jong (ORCID:0000-0002-7620-2704)
Pascal Kaeser (ORCID:0000-0002-1558-1958)
Lab:Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA
SynGO annotation ID:960
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology